磁性微球血管栓塞的实验研究

Vascular Embolization with Magnetic Microspheres:Experimental Studies

本文以磁性微球（ＭＧ－ｍｓ）为栓塞剂进行了实验研究。通过加磁场与不加磁场情况下行兔耳静脉注入￣（９９）ＴＣ标记的ＭＧ－ｍｓ试验、经导管犬肾动脉注入磁微粒（粒径＜１μｍ）和犬肝动脉注入１０～３０μｍＭＧ－ｍｓ的对比研究，显示磁微粒及磁微球有良好的体内磁应性。对１２只犬在加磁场与不加磁场下行肾动脉栓塞，结果有明显差异。对４只犬在加磁场的情况行１０～３０μｍＭＧ－ｍｓ肝动脉栓塞，效果满意。

Embolization of animal vessels with magnetic nucrospheres(MG-ms) showed that MG-ms have good respones to external magnetic field. 12 renal arteric embolization with MG-ms on dogs demonstrated much different result with and without external magnetic field,and satisfied embolization effect was obtained after canine hepatic artery injection of MG-ms (10-30μm) with external magnetic field.