扑感敏片的HPLC测定

HPLC DETERMINATION OF PARACETAMOL,AMINOPHENAZONE AND CAFFEINB IN PUGANMIN TABLBTS

以安替比林为内标物，用反相ＨＰＬＣ法测定扑感敏片中扑热息痛、氨基比林和咖啡因的含量。实验表明，本法能有效地分离杂质，操作简便，重现性好，结果准确。

A reversed-phase HPLC method is described for simultaneous determination of paracetamol,aminophenazone and caffeine in PUGANMIN tablets,using Nova-Pak C18(4μm,4.6mm×20cm)as stationary phase,phenazone as internal standard, methanol-water(45:55) as mobile phase and the detector wavelength at 285nm,This method is simple and accurate.