摘要
以２－溴乙胺氢溴酸盐与对氯苯甲酰氯反应得Ｎ－（２－溴乙基）对氯苯甲酰胺再与吗啉反应得吗氯贝胺，两步收率７４．３％。
An improved process for preparing moclobemide from morpholine and N-(2-bromoethyl)-p-chlorobenzami de(2),obtained from 2-bromoethylamine hydrobromide and p-chlorobenzoyl chloride,has been developed in overall yield of 74.3%.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
1995年第2期50-51,共2页
Chinese Journal of Pharmaceuticals
关键词
吗氯贝胺
对氯苯甲酰胺
合成
moclobemide,N-(2-bromoethyl)-p-chlorobenzamide,synthesis
