摘要
抗早老性痴呆药他克林可由苯胺为原料,经靛红、邻氨基苯甲腈制备。5步反应总收率47%。
Tacrine, a drug for the treatment of Alzheimer's disease, was prepared from aniline via anthranilonitrile in five steps with 47% overall yield.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
1995年第6期246-247,共2页
Chinese Journal of Pharmaceuticals