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两种新型大环内酯类免疫抑制剂 被引量：5

TWO NOVEL MACROLIDE IMMUNOSUPPRESSANTS
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摘要 简要介绍新型大环内酯类免疫抑制剂藤霉素（ＦＫ－５０６）和雷帕霉素的研究与开发、生物理化性质、作用机理、药理和临床试验的进展。 The research and development of two new macrolide immumosuppressants,fujimycin(FK-506) and rapamycin,as well as their biological and physicochemical properties,mechanism of action, pharmacology and clinical trials are briefly reviewed.
作者 杜平中
机构地区 上海医药工业研究院
出处 《中国医药工业杂志》 CAS CSCD 北大核心 1995年第7期330-333,共4页 Chinese Journal of Pharmaceuticals
关键词 大环内酯 免疫抑制剂 藤霉素 雷帕霉素 药理学 macrolide,immunosuppressant,fujimycin(FK-506),rapamycin
分类号 R978.15 [医药卫生—药品] R967 [医药卫生—药理学]
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同被引文献37

  • 1吴洪涛,刘任.新型免疫抑制剂FK506在器官移植中的应用进展[J].国外医学（泌尿系统分册）,1996,16(1):28-30. 被引量：4
  • 2徐积恩.器官移植免疫抑制药物的进展[J].中国医药情报,1996,2(1):49-54. 被引量：2
  • 3Fischman DL, Leon MB,Baim DS,et al. A randomized comparison of coronary-stent placement and balloon angioplasty in the treatment of coronary artery disaese. Stent Restenosis Study Investigators [J].N Engl J Med,1994;331(8):496～501
  • 4Sousa JE, Costa MA, Abizaid A, et al. Sirolimus-eluting stent for the treatment of in-stent restenosis: a quantitative coronary angiography and three-dimensional intravascular ultrasound study. Circulation,2003;107(1):24～27
  • 5Zahn R, Hamm CW, Zeymer U,et al. Safety and Current Indications during ""Real Life"" Use of Sirolimus-Eluting Coronary Stents in Germany. Results from the Prospective Multicenter German Cypher trade mark Registry. Herz,2004;29(2):181～186
  • 6Hoffmann R, Mintz GS, Popma JJ,et al. Chronic arterial response to stent implantation:a serial intravascular ultrasound analysis of Palmamz-Schatz stents in native coronary arteries [J].J Am Coll Cardiol, 1996;28 (5):1134～1139
  • 7Gregory CR, Huie P, Billingham ME, et al .Rapamycin inhibits arterial intimal thicking caused by both alloimmne and mechanical injury. Its effect on cellular ,growth factor, and cytokine response in injured vessels [J]. Transplantation, 1993;55(6):1409～1
  • 8Gregory CR,Huang X, Pratt RE,et al.Treatment with rapamycin and mycophenotic acid reduces arterial intimal thickening produced by mechanical injury and allows endothelial replacement. Transplantation, 1995;59:655～661
  • 9Marx SO, Jayaraman T, Go LO, et al. Rapamycin-FKBP inhibits cell cycle rogulators of proliferation in vascular smooth muscle cells [J].Circ Res, 1995;76(3):412-417
  • 10Burke SE, Lubbers NL, Chen YW, et al. Neointimal formation after balloon-induced vascular injury in Yucatan minipigs is reduced by oral rapamycin[J].J Cardiovasc Pharmacol, 1999;33(6):829-835

引证文献5

二级引证文献11

中国医药工业杂志
1995年 第7期

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