Syntheses of Nucleoside Derivatives Containing Fmocor Trityl-protected Amino Acids

Syntheses of Nucleoside Derivatives Containing Fmocor Trityl-protected Amino Acids

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摘要 Facile direct esterification reactions between 2′,3′-O-isopropylidene-nucleosides and Fmoc- or trityl-protected amino acids %via% N,N-dicyclohexyl-carbodiimide(DCC) mediated condensation are described. These reactions offer a mild and convenient method to synthesize aminoacylated nucleoside derivatives. Facile direct esterification reactions between 2′,3′-O-isopropylidene-nucleosides and Fmoc- or trityl-protected amino acids %via% N,N-dicyclohexyl-carbodiimide(DCC) mediated condensation are described. These reactions offer a mild and convenient method to synthesize aminoacylated nucleoside derivatives.

作者 GUOHui ZOUWu-xin JIQi MAYu-xin MENGJi-ben

机构地区 DepartmentofChemistry

出处《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2005年第4期447-451,共5页 高等学校化学研究（英文版）

基金 SupportedbytheNationalNaturalScienceFoundationofChina(Nos.20072018and20372039).

关键词 NUCLEOSIDE Amino acid ESTERIFICATION 2′ 3′-O-Isopropylidene-nucleoside Nucleoside, Amino acid, Esterification, 2′,3′-O-Isopropylidene-nucleoside

分类号 O626.413 [理学—有机化学] O629.74 [理学—有机化学]

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1Hecht S. M., Acc. Chem. Res., 1992, 25, 545
2Cornish V. W., Mendel D., Schultz P. G., Angew. Chem. Int. Ed. Engl., 1995, 34, 621
3Herranz R., Pichel J. C., Lopez M. T. G., et al., J. Chem. Soc. Perkin Trans.1, 1991, 43
4Malkiewicz A., Sochacka E., Yassin S., et al., Tetrahedron Lett., 1983, 48, 5395
5Reese C. B., Sanghvi Y. S., J. Chem. Soc., Chem. Commun., 1984, 1, 62
6Gao Y., Teruo Matsuura, Meng J. B., Synthetic Communication, 2003, 33(15), 2635
7Wang S. G., Wan Y. Q., Cai Q., et al., Chem. Res. Chinese Universities, 2004, 20(2), 191
8Bain J. D., Wacker D. A., Kuo E. E., et al., J. Org. Chem., 1991, 56, 4615
9Alenka Paquet, Can. J. Chem., 1982, 60, 976
10Leonidas Zervas, Dimitrios M., J. Am. Chem. Soc., 1956, 78, 1359

1赵宝娟,于文全,常俊标,李二通,丁群山,李凤娟,陈光英,王娜.3'-氟-2'-O,3'-C-乙烯基键联并环尿苷的合成与表征[J].高等学校化学学报,2014,35(1):58-62.
2YuGAO WuXinZOU LingWU JinShuiLI JiTaoWANG JiBenMENG.Synthesis of Nucleoside Derivatives Containing Benzophenoxazinone Moiety[J].Chinese Chemical Letters,2004,15(3):300-302.
3杜杨,许雯,姚其正,刘祖亮.5(4H)-吡啶酮并氧化呋咱及其核苷衍生物的合成及结构表征[J].有机化学,2010,30(6):928-932. 被引量：2
4蒙法艳,李美娟,谢娴娴,林翠梧.Synthesis and Crystal Structure of (E)-N,N′- dicyclohexyl-1-(3-(3,4-dihydroxyphenyl)acryloyl)urea[J].Chinese Journal of Structural Chemistry,2012,31(9):1281-1286.
5WEI Ying,LI Xiao-yuan,JING Xia-bin,CHEN Xue-si,HUANG Yu-bin.Preparation of Poly（serine ester）s by Ring-opening Polymerization of N-Trityl Serine Lactone Under Catalysis of ZnEt2[J].Chemical Research in Chinese Universities,2013,29(1):177-182.
6Abdolkarim Zare,Maria Merajoddin,Ahmad Reza Moosavi‐Zare,Mahmoud Zarei.原位生成的Ph_3C^+均相有机催化剂催化4,4'-芳亚甲基-二(3-甲基-1-苯基-1H-吡唑-5-醇)高效合成（英文）[J].催化学报,2014,35(1):85-89.
7Guo, ZX,Yu, J,Yu, J.Surface Modification of Nanometer Silica by N, N'-dicyclohexyl- carbodiimide Mediated Amidation[J].Chinese Chemical Letters,2001,12(10):933-934. 被引量：1
8Hong Ming CHEN,Jian ZHANG,Jian Min MAO,Meng Shen CAI (School of Pharmaceutical Sciences Beijing Medical University, Beijing 100083).STUDIES　ON　NUCLEOSIDES（Ⅲ）．STEREOSELECTIVE　SYNTHESES　OF　TRIAZOLINE－THIONE　NUCLEOSIDES[J].Chinese Chemical Letters,1994,5(6):455-456.
9STEREOSELCETIVE SYNTHESIS OF SOME NUCLEOSIDES[J].Chinese Chemical Letters,1992,3(4):253-254.
10A Convenient Method for Dehydrogenation of Symmetric Hydrazo Compounds[J].厦门大学学报（自然科学版）,1999,38(S1):318-318.

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Syntheses of Nucleoside Derivatives Containing Fmocor Trityl-protected Amino Acids

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