药源性心力衰竭

Drug-induced heart failure

药源性心力衰竭发病急，进展快，必须及时识别和处理。本文综述了临床常用药物引起心力衰竭的发病机理、致病药物、临床特点及防治方法。指出抗心律失常药、抗肿瘤药、降压药、拟交感胺等４大类３５种药物可引起心力衰竭。药物既可导致急性左心衰竭，亦可引起充血性心力衰竭，值得临床用药时警惕。

Drug-induced heart failure happened in abrupt onset and developed rapidly.It must be recogniaed and managed in time.Pathogenesis,pathogenic drug,clinical manifestations,prevention and management of drug-induced heart failure are re-viewed. It has been shown that 35 kinds of drugs,including antiarrhythmics,antitumor agent ,anti-hypertensive drugs,sym-pathomimetic amines and so on,may result in heart failure,then in acute left ventricular failure and congestive heart failure.