妊娠期糖尿病高危孕妇血糖再筛选的价值

Values of Blood Glucose Second Screening for Pregnant Women with Gestational Diabetes Mellitus High Risk Factors

目的探讨妊娠晚期对高危人群血糖进行糖尿病再次筛查的价值。方法选择1999年7月～2001年6月在我院进行围生保健及分娩有糖尿病高危因素的74例孕妇,孕24～28周行50g 葡萄糖负荷试验(GCT),结果血糖均<7.8mmol/L;孕32～34周再次行 50g GCT。结果首次糖筛查均阴性者74人中妊娠晚期50g GCT 复查仍阴性者43人,阳性者31人;阳性者中葡萄糖耐量低减(GIGT)6人,妊娠期糖尿病(GDM)2人。50g GCT 阳性组新生儿病率明显高于阴性组,P<0.01,有统计学意义。结论妊娠晚期对高危人群血糖进行 GDM 再筛查与管理是必要的。

Objective To investigate the value of blood glucose second screening for pregnant women with high risk factors of diabetes melli- tus in late pregnancy.Methods Selecting 74 cases pregnant women with high risk factors of diabetes mellitus who underwent perinatal care and delivered in our hospital from July 1997 to June 2001.50g oral glucose challenge test(GCT)was performed between 24～28 weeks of gesta- tion.The value of blood glucose were all<7.8mmol/L,and the GCT was performed again between 32～34 weeks of gestation.Results Of 74 cases whose first GCT were negative,there were 31 cases who were positive and 43 cases who were negative at the second 50g GCT.of 31 cases with positive resulf there were 6 cases were diagnosed as gestational impaired glucose tolerance(GIGT),2 cases were diagnosed as gestational diabetes mellitus(GDM).The morbidity of newborn of 50g GCT(+)group was obviously higher than that of 50g GCT(-)group(P< 0.01).Conclusions It is necessary that screen GDM at late pregnancy among the population with high risk factors of GDM.