摘要
对不同年龄健康男性被试者卧、立位条件下,心率变异性(heartratevariability,HRV)谱高、低频成分随年龄变化的规律进行研究。结果表明:虽然各年龄组间卧、立位时的静息平均心率并无显著差别,但HRV却随年龄的增长而明显降低,青年组HRV谱高、低频谱峰功率均显著高于中年组、中老年组及老年组(P<0.05或P<0.01);HRV谱低频谱功率、高频谱功率及总功率均随年龄增长呈指数衰减规律。由卧位转为立位时,各年龄组高频谱功率及归一化高频谱参数均显著降低(P<0.05或P<0.01);归一化低频谱参数显著增加,且青、中年组的变化幅度大于中老年组与老年组。上述结果提示,HRV谱成分随年龄增长而降低可用指数函数衰减规律描述;在体位改变过程中,青年组与中年组对1G重力应激的心血管反应性大于中老年组与老年组。
The changes of low frequency(LF_(HRV)) and high
frequency(HF_(HRV)) spectral components ofheart rate
variability(HRV)with age have been studied in 42 healthy male
subjects ranging from20 to 75yr.The results indicated that although
the resting heart rate showed no singificant differ-ence among the
different age groups,the overall HRV declined obviousely with
aging.The resultsof spectral analysis further showed that:①both the
LF_(HRV)and HF_(HRV)of young age group weregreater than those of
middle, elderly and old age groups(P<0.05 orP<0.01),but there were
nosignificant differences of HRV spectral components among the
middle,elderly and old age groups(P>0.05);②the LF_(HRV)and
HF_(HAV)as well as total spectral power
(TP_(HRV))declinedexponentially with aging(P<0.0,and there seems to
be a“threshold phenomenon”forHF_(HRV) decline at about 30yr;③ with
the posture changing from supine to standing,the HF_(HRV)decreased
significantly(P< 0.05 or P < 0.01)in all age groups;the normalized
spectral parameterLF_(HRV,n)increased by 91%,90%,27%,and 40% (P<0.05,
P<0.01 for young,middle,elderly,and old age groups respectively;the
HF_HRV,n decreased by 50%,75%,and 37%(P<0.01)for young,middle,ahd old
age groups respectively,the TP_HRV decreased and LF_HRV to HF_HRV
ra-tio(RF_HRV)increased, but only the changes observed in the young
and middle age groups werestatistically
singificant(P<0.05,P<0.01).The above results showed that the decline
in spectralcomponents of HRV with aging could be described by an
exponential fitting and thecardiovascular responses of young and
middle-aged subjects to the gravitational stress of 1Gwere greater
than those of elderly and old aged subjects.
出处
《中国应用生理学杂志》
CAS
CSCD
1995年第4期317-320,共4页
Chinese Journal of Applied Physiology
关键词
心率变异性
谱分析
年龄
heart rate
variability, spectral analysis
aging,cardiovascular autonomic
regulation