重症急性胰腺炎的介入治疗

Interventional therapy of severe acute pancreatitis

目的评价经胰血管留置导管持续区域灌注生长抑素和抗生素治疗重症急性胰腺炎(SAP)的疗效.方法24例SAP患者采用seldinger技术经右侧股动脉超选择插管至胰腺坏死的供血动脉留置导管,用微泵持续24h灌注生长抑素及抗生素症状消失后拔管.结果灌注治疗后24～48h腹部体征明显改善,7～11d后症状全部消失.结论经胰血管留置导管持续区域灌注生长抑素及抗生素治疗SAP疗效好、病程短、并发症少,值得推广应用.

[Objective] To evaluate the therapeutic efficacy of insertion catheter by pancreatic blood vessel continous regional intra-arterial infusion of somatostatin and antibiotics in the treatment of severe acute pancreatitis (SAP). [Methods] We used Seldinger's method for Twenty-four cases of SAP patients, placing a catheter in the pancreatic regional artery such as gastropyloric artery, irrigating the inflamed area of the pancreas, and infusing somatostatin and antibiontics by continous pumping for 24 h. [Results] Abdom inalsings and pain were apparently relieved after 24~48 h of treatment by regional intra-arterial infusion, disappeared in 7~11 days, the patient fully recovers and leaves hospital three days later. [Conclusion] The therapeutic efficacy of insertion catheter by pancreatic blood vessel continous regional intra-arterial infusion of somatostatin and antibiotics in the treatment of SAP were fine, course of disease short, complication little, worth popularizing and applying.