妇科肿瘤患者生活质量的前瞻性研究

Evaluation on quality of life for gynecologic cancer patient

目的通过调查宫颈癌、卵巢癌、子宫内膜癌患者的生活质量,分析确定妇科肿瘤患者生活质量的影响因素。方法采用FACT-G调查表调查妇科肿瘤患者146例。结果晚期肿瘤患者的身体健康、精神情绪及功能评分均比早期者低(P<0.05)。老年患者(P=0.03),接受高中以上教育者(P=0.004),得到家庭成员支持者(P=0.009)报告的生活质量较高。结论肿瘤的临床分期是影响患者生活质量的主要因素,治疗强度大、文化水平低、家庭/社会帮助少的患者生活质量差,需要更多帮助。

[Objective] The aims of this study were to compare the quality of life (QOL) for gynecologic cancer patients with different cancer sites; to assess the impact of patients′ characteristics, disease parameters, and treatments on the subscale and overall QOL. [Methods] A prospective study was conducted including 146 gynecologic cancer patients. QOL data were collected using the general Functional Assessment of Cancer Therapy (FACT-G) QOL questionnaire. [Results] Advanced stage patients showed significantly poor physical well-being, emotional well-being, and functional well-being, as compared with early stage patients. QOL was reported higher in older patients (P=0.03), above high school education (P=0.004), and with help at home (P=0.009). [Conclusion] Patients with later stage, multi-modality therapy, poor education, and little social support have the most significant impairments and need more support.