中性粒细胞蛋白酶与心肺转流肺损伤
被引量:1
Current concepts of neutrophil proteinases in acute lung injury caused by cardiopulmonary bypass.
摘要
心肺转流肺损伤一直是临床关注的重点。心肺转流过程中,中性粒细胞在肺部积聚、激活并释放出中性粒细胞蛋白酶,参与肺损伤的发生、发展过程中的关键性环节。采用非特异性或特异性的措施抑制中性粒细胞蛋白酶活性,以期预防或减轻心肺转流肺损伤。
出处
《国外医学(麻醉学与复苏分册)》
2005年第2期111-114,共4页
Foreign Medical Sciences(Anesthesilolgy and Resuscitation)
基金
国家自然科学基金资助项目 (3 0 2 712 5 5 )
参考文献24
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二级参考文献30
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1王寿勇,张诗海,姚尚龙.中性粒细胞蛋白酶与心肺转流肺损伤[J].国外医学(麻醉学与复苏分册),2005,26(2):111-114. 被引量:1
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2江宏磊,张慧,郑卫,程元荣.弹性蛋白酶抑制剂Fw 99468抑制动力学的研究[J].海峡药学,2005,17(6):168-170. 被引量:3
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3马国尔,郑金旭.中性粒细胞弹性蛋白酶抑制剂研究现状[J].国际呼吸杂志,2006,26(4):257-259. 被引量:7
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4张爱军,郭继芬,赵玲,赵毅民,王亚芹.LC-MS/MS法检测西维来司他原料药中的降解产物[J].中国新药杂志,2006,15(9):712-715. 被引量:3
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6Yamamoto H;Koizumi T;Kaneki T.Effects of lecithinized superoxide dismutase and a neutrophil elastase inhibitor (ONO-5046) on hyperoxic lung injury in rat[J],2000(02).
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10Nishimura T;Chihara N;Sugai S.Reproductive and developmental toxicity study of sodium N-[2-[4-(2,2-dimethylpropionyloxy)phenylsulfonylamino] benzoyl] aminoacetate tetrahydrate (ONO-5046.Na)(2).Study for effects on pre- and postnatal development in rats, including maternal function,1998(z3).
共引文献7
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1陆志华,高岩.SARS药物治疗和最新研究进展[J].中国药物应用与监测,2003(5):215-217.
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2江宏磊,张慧,郑卫,程元荣.弹性蛋白酶抑制剂Fw 99468抑制动力学的研究[J].海峡药学,2005,17(6):168-170. 被引量:3
-
3马国尔,郑金旭.中性粒细胞弹性蛋白酶抑制剂研究现状[J].国际呼吸杂志,2006,26(4):257-259. 被引量:7
-
4张爱军,郭继芬,赵玲,赵毅民,王亚芹.LC-MS/MS法检测西维来司他原料药中的降解产物[J].中国新药杂志,2006,15(9):712-715. 被引量:3
-
5杨志强,陈小婉,张小兵.中性粒细胞胞外诱捕网络在分泌性中耳炎中的作用及其研究进展[J].中国耳鼻咽喉颅底外科杂志,2023,29(3):110-114. 被引量:1
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6中国医师协会儿童重症医师分会,张育才,洪小杨,卢秀兰,郭予雄,崔云,靳有鹏,杜彦强,刘卓,王义,封志纯.西维来司他钠在儿童重症医学科应用专家共识[J].中国实用儿科杂志,2023,38(5):321-326.
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7陆志华,高岩,徐红.SARS的药物治疗和研究进展[J].中国药师,2004,7(1):15-18. 被引量:7
同被引文献29
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1江宏磊,张慧,郑卫,程元荣.弹性蛋白酶抑制剂Fw 99468抑制动力学的研究[J].海峡药学,2005,17(6):168-170. 被引量:3
-
2马国尔,郑金旭.中性粒细胞弹性蛋白酶抑制剂研究现状[J].国际呼吸杂志,2006,26(4):257-259. 被引量:7
-
3张爱军,郭继芬,赵玲,赵毅民,王亚芹.LC-MS/MS法检测西维来司他原料药中的降解产物[J].中国新药杂志,2006,15(9):712-715. 被引量:3
-
4陆志华.高岩.SARS药物治疗和最新研究进展[J]药物与临床,2003(5).
-
5Yamamoto H;Koizumi T;Kaneki T.Effects of lecithinized superoxide dismutase and a neutrophil elastase inhibitor (ONO-5046) on hyperoxic lung injury in rat[J],2000(02).
-
6Ishikawa N;Oda M;Kawaguchi M.The effects of a specific neutrophil elastase inhibitor (ONO-5046) in pulmonary ischemia-reperfusion injury[J],2003(05).
-
7Yamaguchi K;Aze Y;Shimizu K.Toxicity study of sodium N-[2-[4-(2,2-dimethylpropionyloxy) phenylsulfonylamino] benzoyl] aminoacetate tetrahydrate (ONO-5046.Na) (4). 6-month repeated dose intravenous toxicity study in rats with 1-month recovery test,1998(z3).
-
8Okamoto M;Ide M;Suzuki H.Toxicity study of sodium N-[2-[4-(2,2-dimethylpropionyloxy) phenylsulfonylamino] benzoyl] aminoacetate tetrahydrate (ONO-5046.Na) (5). 6-month repeated dose intravenous toxicity study in dogs with 1-month recovery test,1998(z3).
-
9Nishimura T;Chihara N;Sugai S.Reproductive and developmental toxicity study of sodium N-[2-[4-(2,2-dimethylpropionyloxy)phenylsulfonylamino] benzoyl] aminoacetate tetrahydrate (ONO-5046.Na)(2).Study for effects on pre- and postnatal development in rats, including maternal function,1998(z3).
-
10Wang HG;Shibamoto T;Miyahara T.Effect of ONO-5046, a specific neutrophil elastase inhibitor, on the phorbol myristate acetate-induced injury in isolated dog lung[J],1999(01).
二级引证文献8
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1陆志华,高岩.SARS药物治疗和最新研究进展[J].中国药物应用与监测,2003(5):215-217.
-
2王寿勇,张诗海,姚尚龙.中性粒细胞蛋白酶与心肺转流肺损伤[J].国外医学(麻醉学与复苏分册),2005,26(2):111-114. 被引量:1
-
3江宏磊,张慧,郑卫,程元荣.弹性蛋白酶抑制剂Fw 99468抑制动力学的研究[J].海峡药学,2005,17(6):168-170. 被引量:3
-
4马国尔,郑金旭.中性粒细胞弹性蛋白酶抑制剂研究现状[J].国际呼吸杂志,2006,26(4):257-259. 被引量:7
-
5张爱军,郭继芬,赵玲,赵毅民,王亚芹.LC-MS/MS法检测西维来司他原料药中的降解产物[J].中国新药杂志,2006,15(9):712-715. 被引量:3
-
6杨志强,陈小婉,张小兵.中性粒细胞胞外诱捕网络在分泌性中耳炎中的作用及其研究进展[J].中国耳鼻咽喉颅底外科杂志,2023,29(3):110-114. 被引量:1
-
7中国医师协会儿童重症医师分会,张育才,洪小杨,卢秀兰,郭予雄,崔云,靳有鹏,杜彦强,刘卓,王义,封志纯.西维来司他钠在儿童重症医学科应用专家共识[J].中国实用儿科杂志,2023,38(5):321-326.
-
8陆志华,高岩,徐红.SARS的药物治疗和研究进展[J].中国药师,2004,7(1):15-18. 被引量:7
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