治疗急性呼吸衰竭的又一重要手段——无创正压通气

Non-invasive positive pressure ventilation——a valuable method for treating acute respiratory failure

目的评价无创正压通气(NIPPV)治疗不同病因导致急性呼吸衰竭的价值.方法 43例急性呼吸衰竭患者,分全程无创组(30例)和无创-有创组(13例),比较全程无创组患者治疗前与治疗后2～8小时的PaO 2;比较全程无创组中COPD患者治疗前与治疗后2～8小时的PaCO 2;比较两组的APACHEⅡ分值;比较全程无创组中脱机成功与失败的APACHEⅡ分值.结果全程无创组治疗前与治疗后2～8小时的PaO 2有显著差异;COPD患者治疗前与治疗后2～8小时的PaCO 2有显著差异;两组间APACHEⅡ分值有显著差异,全程无创组中脱机成功与失败患者的APACHEⅡ分值有显著差异.结论 NIPPV是治疗不同病因急性呼吸衰竭安全而有效的手段.

Objective To evaluate the significance of non-invasive positive pressure ventilation (NIPPV) in treating acute respiratory failure caused by various causes.Methods Forty-three cases with acute respiratory failure were divided into two groups,NIPPV group (30 cases) and NIPPV-IPPV(invasive positive pressure ventilation)group (13 cases).To compare the differences between PaO_2 before NIPPV and after NIPPV in NIPPV group; between PaCO_2 before NIPPV and after NIPPV in 14 COPD patients; and between APACHEⅡscore in NIPPV group and NIPPV-IPPV group; between APACHEⅡscore in the weaned from NIPPV patients and the unweaned in NIPPV group.Results There were significant differences in PaO_2 before and after NIPPV.There was significant difference in PaCO_2 before and after NIPPV in 14 COPD patients.There were significant differences in APACHEⅡscore between the weaned from NIPPV patients and the unweaned in NIPPV group and between the two groups.Conclusions NIPPV is a safe and effective method in treating acute respiratory failure caused by various causes.