骨质疏松与老年妇女髋部骨折

Risk Prediction of Osteoporotic Hip Fracture in Elderly Women

目的探讨老年妇女骨质疏松性髋部骨折的危险性因素,为预测老年妇女骨质疏松性髋部骨折提供依据。方法以髋部骨折老年女性患者及保健体检的老年妇女各30例为研究对象,分为病例组和对照组,其中病例组来自2002年2月～2004年2月,深圳市人民医院骨科共收治老年女性骨质疏松髋部骨折患者,对照组来自同期在该院进行社区保健体检的健康老年妇女。测量所有样本髋部骨密度(BMD)(病例组为健侧,对照组为左侧)、颈干角(NSA)、左手握拳力;根据身高体质量算出体重指数(BMI);确定个人及家族女性骨折史。通过logistic回归分析及判别分析,进行统计学处理。结果老年妇女骨质疏松性髋部骨折的危险因素为:ward区BMD、NSA、BMI、左手握拳力。结论ward区BMD、NSA、BMI、左手握拳力减弱为老年妇女骨质疏松性髋部骨折的危险性因素。

Objective To study the relationship between the osteoporotic hip fracture in elderly women and the risk factors,we established a equation to predict the probability of the osteoporotic hip fracture in elderly women.Methods The women diagnosed as the osteoporotic hip fracture were regarded as the case and the other women for physical examination were regarded as the control.Based on the standards of fit and rejection,30 cases and 30 controls were introduced into the study.We used the Dual Energy X-ray Absorptiometry(DEXA) bone densitometry to examine the bone mineral density(BMD) of hip and neck-shaft angle(NSA),measured the left grip strength,then calculated the body mass index(BMI) according to the height and weight.Meanwhile,we inquire about the individual history and the family history of osteoporotic fracture.By logistic regression analysis,the risk factors were screened,the regression coefficients were standardized and the contribution of the risk factors was compared.By discriminant analysis,we established a equation for prediction.Results The BMD of the ward area,the NSA,the BMI and the left grip strength were the risk factors of the osteoporosis hip fracture in elderly women.Conclusions The risk of osteoporotic hip fracture in elderly women is connected with the BMD of the ward area,the NSA,the BMI and the left grip strength.