天津市10家医院肺炎链球菌下呼吸道感染临床分析

The clinical analysis of low respiratory tract infection with S.Pneumoniae in ten hospitals of Tianjin

目的:分析天津市10家医院近3年来肺炎链球菌下呼吸道感染患者的临床情况及对抗生素的敏感情况。方法:随机统计近3年下呼吸道感染患者共计1608例次,应用计算机统计软件SPSS1.0进行数据统计。结果:在1608例次感染中,肺炎链球菌感染39例次,占2.43%,在各类细菌感染中排列第11位;社区感染共计735例次,其中肺链感染36例次,占社区感染的4.90%,在社区感染中排第4位,与国内外报道有一定的差别。结论:(1)下呼吸道感染患者痰培养肺炎链球菌阳性率较低,与国内外报道不一致,可能有地区差别或与培养方法和滥用抗生素有关。(2)肺炎链球菌以社区感染为主,好发于冬季,老年人易患,死亡率较低(2.56%)。(3)药物敏感试验与临床有效率不完全一致,药敏与临床治疗相结合是非常重要的。(4)此分析对天津市肺炎链球菌感染患者抗生素的选择可能有一定的帮助。

Objective:The clinical status of low respiratory tract infection sufferers who infect S.Pneumoniae and their sensitivities to the antibiotics was analysed in ten hospitals of Tianjin in recent three years. Methods:There are 1 608 cases of low respiratory tract infection sufferers from ten hospitals of Tianjin which were collect in random way and dealt statistically using the SPSS 1.0 computer statistical software. Results:In the 1 608 infection cases there are 39 cases of S.Pneumoniae infection account for 2.43%listed at 11th in various bacterial infection In the 753 community infection cases there are 36 cases of S.Pneumoniae infection account for 4.90%listed at 4th in community infection. So it has some differences with domestic and foreign reports. Conclusion:1The positive ratio of phlegmy culture for S.Pneumoniae infection sufferer in the ten hospital of Tianjin is low which is not consistent with domestic and foreign reports. It may have some relations with regional differences method of culture and the abuse of antibiotics.2 The S.Pneumoniae infection has some characteristics the main kind of the infection is the community infection it usually happens in the winter oldsters often suffer it its death-ratio is low2.56%.3 The drug sensitivity test is not consistent with the clinical availability ratio while it is very important to combine the result of the drug sensitivity test with the clinical treatment.4 This analysis may help the choice of antibiotics for S.Pneumoniae infection sufferers lived in Tianjin.