妊娠期妇女生殖道感染与妊娠不良结局分析

An analysis of reproductive tract infection and pregnancy outcome in pregnant women

目的:探讨妊娠期妇女生殖道感染(reproductivetractinfection,RTI)的类型及对妊娠不良结局的影响。方法:回顾性分析2003年1月-2004年12月在我院住院孕产妇共5499例,进行生殖道病原菌检测,随机分为RTI患者(感染组)与正常孕产妇(对照组),分析妊娠合并生殖道感染与围产期并发症的关系。结果:在5499例围产期妇女中,RTI总患病率为28.23%,细菌性阴道病患病率13.18%,外阴念珠菌阴道病患病率11.16%,滴虫性阴道炎患病率1.87%,宫颈沙眼衣原体感染患病率1.42%,妊娠合并梅毒患病率0.27%,淋病患病率0.15%,尖锐湿疣患病率0.18%。感染组与对照组的死胎率分别为1.10%、0.13%(P<0.01),胎膜早破率分别为15.12%、4.67%(P<0.01),早产率分别为2.30%、0.20%(P<0.01),胎儿窘迫率分别为6.24%、2.67%(P<0.01),新生儿窒息率分别为2.23%、0.67%(P<0.01)。结论:预防妊娠期妇女生殖道感染应早期开展RTI常规检测和治疗。

Objective To study the prevalence and pregnancy outcome of reproductive tract infections(RTI)in pregnant women.Methods A retrospective analysis was conducted among 5 499 pregnant women who were examined for RTI between January 2003 and December 2004. 1 553 RTI patients(RTI group) and 1 300 normal pregnant women(control group) were randomly selected and the relationship of RTI and complication were analysed.Results The prevalence of RTI was 28.23%,in which of trichomoniasis、vulva vaginal candidiasis(VVC)、bacterial vaginosis(BV)、 chlamydia trachomatis(CT)of cervix,syphilis,neisseria gonorrhoeae and condy1oma accuminatawere 1.87%,11.16%,13.18%,1.42%,0.27%,0.15% and 0.18% respectively.The rate of fetal death(1.10%),premature rupture of membranes(15.12%),preterm labor 2.30%),abnormal amniotic fluid(6.24%)and neonatal asphyxia(2.23%)were significantly higher in RTI group than that in control group respectively(0.13%,4.67%,0.20%,2.67%and 0.67%,P<0.05.Conclusion Routine screening and therapy of RTI in pregnant women should be carried out earlier.