职业接触抗癌药的女护士职业危害调查

The survey on female nurses professional dangerous about contacting with antineoplastic medicine

目的:了解职业接触抗癌药物护士的职业危害状况。方法:回顾性调查职业接触抗癌药物女护士的月经史、妊娠经过结局以及机体不良反应。结果:接触组的月经周期异常、妊娠并发症发生率、妊娠贫血发生率、胎儿宫内发育迟缓高于对照组,差异有显著性,机体对抗癌药物产生的不良反应发生率较高。结论:职业接触抗癌药物对女性月经及生育产生不良后果,机体在抗癌药物刺激下,不良反应发生率较高,管理部门应予以重视,加强对职业接触抗癌药物护士的职业安全保护。

Objective:Study the professional endanger situation of nurses who contact with antineoplastic medicine.Methods:The retrospective cohort study was carried out to study the menstruation history,process and result of pregnancy, and body adverse reaction of female nurses who contact with antineoplastic medicine.Results:The rates of disorder of menstrual cycle, pregnancy combination,anemia during pregnancy and fetal IUGR(Intrauterine Growth Retardation)were higher than those of control group. The differences were significant. The incident rate of body adverse reaction against antineoplastic medicine was higher.Conclusion:Professional contact with antineoplastic medicine may cause adverse results of female menstruation and reproduction. Under the stimulation of antineoplastic medicine,body adverse reaction rate was higher.The administration should take into account and strengthen the professional safety protection for nurses who professional contact with antineoplastic medicine.