胃康宁治疗糜烂性胃炎临床应用和实验研究

Clinical and experimental studies on erosive gastritis treated with Weikangning powder

本文用中药胃康宁治疗糜烂性胃炎５４例，并与用西药甲氰米哌治疗的２０例作对照，结果表明，两组病人服药４周后经胃镜检查，结果中药组糜烂治愈率为９０．７％，西药组为６５％，两组比较有显著差异（Ｐ＜０．０１）。通过对盐酸所致急性胃炎和消炎病所致胃粘膜损伤的大鼠实验表明，胃康宁对大鼠胃粘膜有很好的保护作用。

74 patients with erosive gastritis were divided two groups. 54 patients were treated by Weikangning powder as Chinese herb (CH) group,and 20 patients by cimetidine as western medicine (WM) group. After 4 weeks' treatment the gastroscopic examination were given and the results showed that the curative rate in CH group was 90. 7%,but 65% in WM group. They havesingnificant difference (P<0.01 ). The rats with acute gastritis induced by hydrochloric acid andwith the damage gastric mucosa induced by indomethacia were treated by Weikangning powder.The experimental results manifested that the Weikangning powder has a quite good protection forthe gastric mucosa of rats.