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红宝联合干扰素治疗慢性乙型活动性肝炎的研究

A study of mocrea combined interferon in the treatment of chronic active hepatitis B
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摘要 慢性乙型活动性肝炎51例,随机分为2组,治疗组25例,每次服红宝(枸杞多糖)2粒,每日2次,干扰素α-2b,每次300万U,每周3次,连用16周.对照组26例,每次服肝必复140mg,每日3一次,连用16周,治毕6个月后随访.结果显示治疗组HBVDNA和HBeAg的阴转率明显高于对照组,分别为72%和26%,11.5%和15.4%(P<0.001),总有效率达68%,不良反应轻. Fifty one patients with chronic active hepatitis B were randomly divided into two groups. The 25 patients were treated with mocrea (lytium barbarum polysaccharides dose 2 pills po. bid) and interferon α-2b (3 million units tiw. )for 16 wk in the treated group. Other similar 26patients received ganbifu 140mg. po. tid for 16 wk served as control. Follow-up study at 6th monthsfter completion of treatment. Results showed that seroconversion to negative HBV DNA and HBeAg in the treated group were marked higher than those in the control group (72% and 76% vs11.5% and 15. 4%. respectively P<0. 001 ). The total effective rate was 69%. Adverse reactionswere mild.
出处 《中国中西医结合脾胃杂志》 1995年第2期84-86,共3页
关键词 枸札多糖 干扰素 慢性 乙型活动性肝炎 乙型肝炎 Lycium barbarum polysaccharides Intcrferon α-2b
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