夜咳宁口服液治疗小儿咳嗽的临床与实验研究

Clinical and Experimental Study on Oral Liquor Night-Cough Tranquiller in Treating Infantile Cough

本研究用中药夜咳宁口服液治疗小儿咳嗽１２８例，痊愈６４例，有效５８例：总有效率为９５．３１％，对照组服伤风止咳糖浆加头孢氨苄胶囊１００例，痊愈３９例，有效４２例，总有效率为８１．００％，两者比较有显著性差异（Ｐ＜０．０５）。实验研究表明，夜咳宁口服液有显著的化痰、止咳、镇静等药理作用，无毒性反应。

Oral Liquor of Night-Cough Tranquiller(NCT)was used in treating infantile cough and 128 patients have been treated.The result revealed that the total effective rate was 95.3%.In comparing with other group of patients treated with the common cold cough syrup and Caps.cephalexini,the latter has a clinical effective rate of 81.0%.A significant difference existed between the abovementioned two groups (p<0.05).According to the animal experiment,the NCT has some outstanding pharmacologic functions such as anti-tussive function,phlegm reducing and sedation,etc.While the LD50 of NCT has not been detected which indicated that this preparation has negligible side effect.