食管癌舌脱落细胞变化及其与中医辨证分型关系的初步研究

Preliminary Study on Relationship between Syndrome Differentiation of Esophageal Cancer and Changes of Exfoliated Cells of Tongue Coating

本研究应用脱落细胞学技术，对６３例食管癌患者进行了舌脱落细胞检测。结果发现：食管癌患者较常见异常角化细胞，而角化细胞却减少，与健康对照组比较差异有显著性（Ｐ＜０．０５）；其中气虚阳微证以角化前细胞增多为主，阴虚证以完全角化细胞增多为主，而痰湿证和血瘀证两组则角化前细胞和完全角化细胞均增多，各组之间相互比较差异显著（Ｐ＜０．０５）。食管癌舌脱落细胞的变化，为舌诊早期诊断食管癌提供了客观依据。

Exfoliated cells of tongue coating of 63 esophageal cancer(EC)cases have been investigated by applying exfoliate cytologic examination,which showed that abnormal cornified cells were commonly seen while they were less in the patients of EC than those in the healthy group,and their difference was significant (P<0.05),It showed an increase mainly in the number of pro-cornified cells in the patient of the Qi-Yang Deficiency group,an increase mainly in completely cornified cells in the Yin Deficiency and an increase in both pro-cornified cells and completely cornified cells in Phlegn-Dampness and blood Stasis patients.The difference among four groups was significant (P<0.05).The changes of exfoliated cells of tongue coating provided an ojective index for the early diagnosis of EC.