摘要
为了解抗脑血栓注射液抗实验性动脉血栓的作用，用Ｃａｔｔａｎｅｏ制作动脉血栓动物模型进行观察。结果耳静脉滴注抗脑血栓注射液后，模型动物的血栓重量、凝血酶原时间延长程度、全血粘度降低程度和血栓素Ｂ２（ＴＸＢ２）浓度均较生理盐水对照组有所降低，Ｐ均＜０．０５～０．０１。认为抗脑血栓注射液的抗血栓作用是通过降低全血粘度和ＴＸＢ２浓度，从而抑制血小板的聚集和释放反应的结果。
Anti-Cerebral Thromboembolism Injection(ACTI),applied intravenously in Cattaneo's animal model of arterial thrombosis,could significantly reduce the weight of thrombus,blood viscosities, plasma TXB2 level and delay the prothrombin time,compared to control group(P<0.05).From this trial,it was indicated that ACTI's reducing thrombosis action was the result of inhibiting aggregation and releasing of platelets through reducing whole blood viscosities and TXB2 level.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
1995年第7期424-425,共2页
Chinese Journal of Integrated Traditional and Western Medicine
关键词
抗脑血栓注射液
血液流变学
血栓形成
Anti-Cerebral Thromboembolism Injection
hemorheology
thrombosis
