复春片合并放射治疗鼻咽癌临床研究

Clinical Study on Effect of Combined Treatment of Fuchunpian with Radiotherapy on Nasopharyngeal Carcinoma

本研究对６０例鼻咽癌患者采用双盲随机分组法，对服用复春片合并放射治疗鼻咽癌的预后进行了前瞻性对照研究。结果提示，两组患者的１、３、５年生存率无显著性差异，而服用复春片组患者的肿瘤血性转移率（３６．７％）高出对照组患者（１０．０％）２．６７倍，提示在现有剂量条件下，复春片对鼻咽癌细胞可能尚无明显放射增敏作用。因而认为不宜将复春片常规单独或与放射合并应用治疗鼻咽恶性肿瘤。

The study based on the clinical prospective trial of 60 cases of nasopharyngeal carcinoma treated with combined treatment of radiotherapy and Fuchunpian in our hospital from September,1988 to January,1990.Results of clinical data of 5 years follow-up showed that Fuchunpian not only couldn't enhance the radiosensitivity of patients,but also increase the blood metastatic potency,the metastatic rate of patients treated with Fuchunpian(36.7%) was 2.67 times higher than that without it(10.0%).Therefore,it was considered that use Fuchunpian as a routine either administrated alone or combined with radiotherapy in treatment of nasopharyngeal carcinoma is not suitable.