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胰岛素样生长因子与子宫内膜及子宫内膜异位症的关系

Correlation of Insulin-like Growth Factor with Endometrium and Endometriosis
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摘要 目的:探讨胰岛素样生长因子(IGFs)与子宫内膜及子宫内膜异位症(EMs)的关系。方法:查阅文献,进行综述。结果:IGFs及其受体和胰岛素样生长因子结合蛋白(IGFBPs)在子宫内膜发生生理性和病理性改变时其表达也发生变化。EMs患者在位内膜和异位内膜的IGFs及其受体和IGFBPs表达强度不同,且其在腹水中的表达强度也与对照组不同。结论:胰岛素样生长因子对子宫内膜的生长和分化有调控作用;它可能参与了EMs的病理发生过程。 Objective:To explore the correlation of insulin-like growth factor (IGFs) with endometrium and endometriosis (EMs).Methods:Looking up literatures and summarizing them.Results:The expression of IGFs and insulin-like growth factor binding protein (IGFBPs) varied with the physiological and pathological changes in endometrium.Compared with control group,the expression of IGFs,its receptor and IGFBPs differed in normal or dystopic endometrium and ascites.Conclusion:IGFs plays a role in regulating growth and differentiation of endometrium.It may involve in pathogenesis of EMs.
作者 伊丽奇 斯日古楞
机构地区 内蒙古自治区医院妇产科
出处 《内蒙古医学杂志》 2005年第7期617-620,共4页 Inner Mongolia Medical Journal
关键词 胰岛素样生长因子 胰岛素样生长因子结合蛋白 子宫内膜 子宫内膜异位症 Insulin-like growth factor (IGFs) Insulin-like growth factor binding protein (IGFBPs) Endometrium Endometriosis
分类号 R711.71 [医药卫生—妇产科学]
  • 相关文献

参考文献15

  • 1李晖,何援利.胰岛素样生长因子-1与胰岛素样生长因子结合蛋白-1在妇产科临床应用的研究进展[J].陕西医学杂志,2004,33(2):153-155. 被引量：7
  • 2徐向荣,周馥贞.胰岛素样生长因子-Ⅱ在人早孕期绒毛和蜕膜中的表达[J].中国实用妇科与产科杂志,2003,19(2):110-111. 被引量：1
  • 3Jones J I, clemna ons DP.Unsulin-lick growth factors and tbeir binding proteins biological action[J].Endocr Rev,1995,16(1):3.
  • 4M. Kitazawa,L.F.suem,J.C.Irwin,Haman deciduas and decidualized endometrial srtomal cell(ESC).but not trophoblast.express IGF binding protein-related protein-I(IGFBP-rp-I)which is regulated by IGF-Ⅱ[J].Soc Gynecol Invest.1998.5(1):113.
  • 5Giudice LC ,Mark SP, Lrwin JC. Paracrine actions of insulin - like growth factors and binding protein - 1 in non - pregncmt human endometrium at the decldual - trophoblast interface [ J ] .Reprod Immunol. 1998.39 ( 1 - 2) : 133.
  • 6叶明珠,林影,郑桂英.子宫内膜胰岛素样生长因子系统的基因表达[J].国外医学（妇产科学分册）,2003,30(5):284-286. 被引量：3
  • 7Anemo - Menopause - Center, 12 Rue de France, F - 06000 Nice, Framce, Department of Gynecology and obstetrics, university HospitaI,Es,sen,Germany. IGF- Ⅰ in gynecology and obstetrics: update 2002 [ J ]. Maturitas,2002,41 (suppl. 1 ) : S65 - S83.
  • 8Rahindra N. Roy,Anthony Cecuui,et al. Quantitative profiles of the transcripts of Insulin - like growth factors and their receptors in normal and meoplastic endometrium [J ] .Soc Gynecollnvest,1998,5(1) :112A.
  • 9Chang SY, Ho Ys. lmmunohistochemical analysis of insulin - like growth factor 11 in endometriotic tissue and endometrium[J ] .Acta Obstet Gyneol Scand, 1997,76(2) : 112.
  • 10梁元姣,梅巧娣,吴效科.胰岛素样生长因子-1在妇科疾病中的作用[J].医学研究生学报,2004,17(1):83-86. 被引量：14

二级参考文献49

  • 1舒强,王桂兰,董建军,蒋玲,陈福琴.绝经后骨质疏松与胰岛素样生长因子[J].中国骨质疏松杂志,1999,5(1):28-31. 被引量：27
  • 2[1]Druckmann R, Rohr UD. IGF-1 in gynaecology and obstetrics:update 2002[J]. Maturitas,2002,41(Suppl.1):S65-S83.
  • 3[2]Jones JL, Clemmons DR.Insulin like growth factors and their binding protein:biological actions[J].Endocr Rev,1995,16(1):3-34.
  • 4[3]Dufourny B,Ablas J, van Teeffelen HA et al. Mitogenic signaling of insulin like growth factor Ⅰ in MCF-7 human cancer cells requires phosphatidylinositol 3 kinase and is independent of mitogen-activated protein kinase[J].J Biol Chem,1997,272(3):1163-1171.
  • 5[4]Gamero P, Sornay-Rendu E, Delmas PD. Low serum IGF-1 and occurrence of osteoporotic fractures in postmenopausal women[J]. Lancet,2000,355(9207):898-899.
  • 6[5]Gomez JM, Mourot B, Fostier A et al. Growth hormone receptors in ovary and liver during gametogenesis in femal raibow trort (Oncorhynchus mykiss)[J].J Reprod Fertil, 1999,115(2):275-285.
  • 7[6]Lucy MC, Bilby CR,Kirby CJ et al. Role of growth hormone in development and maintenance of follicles and corpora lutea[J].J Reprod Fertil,1999,54(1):49-59.
  • 8[7]Laron Z, Silbergeld A, Klinger B. Hyperandrogenism induced by insulin-like growth factor-1 (IGF-1) treatment of two girls with Laron syndrome[J].Clin Endoctinol,1998,10(1):75-79.
  • 9[8]Strawn EY,Novy MJ, Burry KA et al. Insulin-like growth factor-1 promotes leiomyoma cell growth in vitro[J].Am J Obstet Gynecol,1995,172(6):1837-1844.
  • 10[9]Olive DL pritts EA, Treatment of endometriosis[J].N Eng J Med,2001,345(4):266-275.

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内蒙古医学杂志
2005年 第7期

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