热毒平治疗内毒素性高热的临床研究

Clinical Study on ReDuPing In the Treatment of Endotoxic Hyperpyrexia

本文将62例内毒素性高热患者,随机分为热毒平组40例,对照组22例.热毒平组用热毒平胶囊治疗,对照组用抗生素治疗,疗程均为3日.结果发现,不论在发热消退时间、血浆内毒素的消除及疾病转归方面热毒平组的疗效显著高于对照组.同时发现,服用热毒平无毒副反应.文中对血浆内毒素的产生途径及危害性、内毒素性疾病的中医药治疗方法及本项研究病例选择依据、观察时限确定等问题进行了讨论.

62 patients with endotoxic hyperpyrexia were randomly into two groups:40 cases in the ReDuPing treatment group and 20 cases in the control group treated with antibiotic. Drugs were administered to all patients for 3 days. The results showed the effects of ReDuPing group were more significant than that of antibiotic group in dropping temperature, eliminating endotoxin in plasm and restoring disease. It was also found that ReDuPing is non-toxic and has no side-effects. In the paper, the authors discussed the way producing plasmic endotoxin, the harm to health caused by endotoxin and the methods of treating endotoxic diseases with TCM,as well as the basis for choosing cases and the determination of the observed time in this study.