中药雾化吸入治疗中度哮喘临床和实验初步研究

Clinical and Experimental Studies on Moderate Bronchial Asthma Treated by Chinese Herbal Aerosol Inhalation

本文以中药雾化吸入的形式,观察其对34例中度支气管哮喘的治疗作用,结果见临床控制及显效率64%,总有效率90%;治疗后患者PEFR和EOS有显著改变(P<0.05).动物实验见对豚鼠乙酸胆碱一组胺性哮喘具有平喘作用(P<0.01),体外对微粒体脂质过氧化物的形成具有抑制作用(P<0.05～0.01).

34 cases of bronchial asthma were treated with Chinese herbal aerosol (volatile oil extracted from Flos Magnolia, Ephedrae, etc. ). Results showed that 64% of the patients got a marked effectiveness and the total effective rate of the patients was 90%. After treatment, PEFR was markedly increased and EOS was markedly decreased (p<0. 05). Experiments on guinea pigs showed that Chinese herb inhalation can relieve asthma caused by histamine phopshate-acetylcholine and inhibit the lipid peroxidation of microsome in vitro.