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SCF-Skp2与肿瘤关系的研究 被引量:1

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摘要 肿瘤的发生与细胞周期的失控密切相关,泛素蛋白酶体(SCF)途径降解细胞周期调控因子。而S期激酶相关蛋白2(Skp2)是泛素连接酶复合物的底物识别序列,对细胞周期G1期关卡起调控作用,在多数恶性肿瘤中表达增高。研究发现SCF-Skp2与肿瘤的进程、治疗、预后均有密切关系。
作者 李云祥 苟欣
出处 《中国全科医学》 CAS CSCD 2005年第14期1199-1201,共3页 Chinese General Practice
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参考文献20

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共引文献12

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