鼻腔恶性黑色素瘤24例分析

Malignant Melanoma of Nasal Cavity :Report of 24 Cases

鼻腔恶性黑色素瘤为临床难治疾病之一。对１９７１～１９９１年的临床和病理资料进行回顾性分析和随访，发现鼻腔恶性黑色素瘤２４例，占同期耳鼻咽喉科住院患者的０．２％。其病理特点为在不同的瘤细胞内可见典型的前黑色素体，注意寻找瘤细胞内细小的黑色素颗粒，可避免误诊。手术仍为治疗本病的首选方法，亦可配合放疗，术后创面加激光照射处理，疗效较佳。２０例死亡，存活１～４年；４例健在，分别生存４、３、３、２年。

The malignant melanoma of nasal cavity is one of the refractory diseases.The malignant degree and the recurrent rate of this disease are high.And it is very easy to make misdiagnosis.This article reviewed the clinical and pathological data of malignant melanoma of nasal cavity for 20 years from 1971 to 1991.All the patients were followed up.We found that there were altogether 24 cases of this disease which covered 0.02% of all the inpatients during that period of time.The pathological char-acteristics of this tumor sliowed that there was a typical fore-melanin body in different tumor cells.If we pay attention to the minor and grained melanin,Tnisthagnosis can be avoided.Surgery is the first choice for this disease.And the post-operative radiotherapy,laser therapy gives a better result.