硬膜外用药对癌痛镇痛的初步观察

Cancer Pain Relief by Epidural Injection of Morphin

报道５２例中重度癌痛病人应用硬膜外用药镇痛，平均显效时间７．１±３．４分钟，平均缓解时间为５．８±２．８小时，有效率为１００％（５２／５２）。本文报告为一次硬膜外用药结果，结果表明：年龄、性别、肿瘤种类、癌痛部位对硬膜外用药镇痛效果无明显影响，０．０１％与０．０２％吗啡溶液用于硬膜外对癌痛镇痛作用肯定。硬膜外用于癌痛镇痛中主要不良反应为嗜睡（２７％）、头晕（９．６％）、憋气（７．８％）、尿潴留（３．８％）、下肢瘫软（２８％）。

ifty-two patients who had moderate or severe cancer pain were treated with morphine or other drugs by epidural injection. The result indicated that the pain was relieved in 7. 1±3. 4 minutes and lasted for 5. 8±2. 8 hours. The effective rate was 100%. Neither age sex of patients nor kind and location of cancer had any impact on the anangesic effect. The effect of 0. 02% and 0. 01% morphine solution on cancer pain relief was definite. The main side effects of this therapy were somnolence (27%), dizziness (9. 6%), shortness of breath (7. 8%), retention of urine (3. 8%), weakness of legs (28%).