非根治术或加放疗治疗Ⅰ、Ⅱ期宫颈癌

Treatment of Stage Ⅰ and Ⅱ Cervical Carcinoma by Non-radical Operation with or without Radiation

对全子宫加双侧附件切除或术前后补加放疗的１１８例宫颈癌（临床Ⅰ期７１例、Ⅱ期４７例）的疗效进行总结。结果，单纯手术组（２７例）５及１０年生存率为８机及６３％，补加放疗组（９１例）为７６％及６０％，组间比较Ｐ皆＞０．０５。与本院１７５例宫颈癌根治术相比，５及１０年生存率在Ⅰ期差别有显著性（Ｐ＜０．０１），在Ⅱ期差别无显著性（Ｐ＞０．０５）。放疗在术前或术后对生存无影响（Ｐ＞０．０５）。从本组有限的病例看，建议原位癌早期浸润应按０期癌对待只行全宫切除术，其它Ⅰ期癌应行根治术，Ⅱ期癌可行非根治手术并补加放疗。

From 1979 to 1984,118 patients with stageⅠ(71 cases) and Ⅱ (47 cases)cervical carcinoma underwent non-radical surgical teratmtent (extensive hysterosalpingo-oophorectomy) with or without radiation in our hospital.The 5-and 10-year survival rates were 85% and 63% in the group of surgery alone(27 cases).The same rates were 76% and 60% in the patient group treated with additional radiation (91 cases).The difference was not remarkable with p value greater than 0.05.Comparing with the 175 patients with stage Ⅰ and Ⅱ cervical carcinoma who were treated by radical surgery in our hospital,there was significant difference in the 5- and 10-year survival rates in patients with stageⅠ disease (P<0.01),but not in those with stage Ⅱ disease(P>0.05).There was no difference in survival rates either the radiation was given before or after surgery (P>0.05).The authors suggest that cervical carcinoma in situ with early infiltration should be treated with hysterectomy alone and stage Ⅰ cervical carcinoma with radical surgical treatment,whilst stage Ⅱ cases should be treated with non-radical operation plus radiation.