128例甲状腺癌死亡病例临床分析

Analysis of 128 Patients with Thyroid Cancer Who Succumbed after Treatment

报告自１９５４～１９８５年共外科治疗９３７例甲状腺癌病人，其中死亡１２８例，死亡率为１３．６６％。全部死亡病例中乳头状癌，滤泡癌，髓样癌及间变癌的死亡率分别为１０．２８％，１５．０９％，２５．９３％及７５．０％。分化型癌与低分化型癌死亡率差异显著。颈淋巴结转移，远处转移，腺外及周围组织侵犯皆与死亡率有关。其中７０例（５４．２６％）因侵犯局部重要器官或淋巴结转移致死，５８例（４５．３１％）因远处转移致死。肿瘤局部侵犯及血行转移是主要致死因素。

A total of 937 patients with thyroid carcinoma were treated with surgery between 1954 and 1985.128 patients died within an average of 4.97 years after surgical diagnosis was made. Of the 128 fatalities,77 were of the papillary (10.28%) in histologic type,16 follicular(15.09%),14 medullary(25.93%),and 21 anaplastic (75.0%).The grade of malignancy in terms of differentiation affected significantly the fatality which also was closely related with cervical lymphnode involvement, distant metastasis, invasion of surrounding structures. In this series 70cases died (54.26%) of invasion of vital structures and nodal metastasis, 58 of distant metastasis (45.31%).