DAKO－M1在正常组织和肿瘤的表达

Distribution of DAKO-M1 in Tumors and Normal Tissue

应用ＬＳＡＢ法免疫组化技术，研究抗ＤＡＫＯ－Ｍ１单抗在人体２７个部位正常组织，１９６例上皮性肿瘤和５２例非上皮性肿瘤的表达。结果表明，ＤＡＫＯ－Ｍ１可作为各种正常上皮细胞、腺癌及何杰金氏淋巴瘤Ｒ－Ｓ细胞的良好标志物。ＤＡＫＯ－Ｍ１在腺癌组织的定位分布对判断分化程度有参考意义。

DAKO-M1 was illustrated with immunohistochemical LSAB tech nique in 196 epithelial tumors,52 non-epithelial tumors,and tissues from 27 sites of human body.The findings suggest that DAKO-M1 can serve as a good marker of various epithelium,adenocarcinoma and Hodgkin's lymphoma and it can help to differentiate epithelial tumor from non-epithelial ones,adenocarcinoma from other epithelial tumors.The localization of DAKO-M1 in adenocarcinoma is of significance for us to determine the cellular differentiation and the outcome assess.