星形细胞瘤与胚脑星形细胞的电镜对比观察

A comparison between astrocytoma cells and the developing astrocytes in human embryo brain by electron microscopy

用光镜及电镜观察了６０例脑星形细胞瘤及８例早期人胚脑及神经管组织。结果显示：瘤细胞超微结构可分五型，即未分化细胞、前星形细胞、星形细胞、胖细胞及瘤巨细胞。与胚脑发生中的星形细胞相比较，瘤细胞有类似发生中星形细胞相应各个阶段的分化。不同之点是瘤细胞常呈不典型性，形态畸变、染色质增多、核浆可呈不同步分化等。基于上述观察，我们对传统的星形细胞瘤命名及分类作了评价，并对分类提出看法。

0 cases of astrocytoma of brain and 8 human embryo brains were studied with light and electron microscopy. The 5 types of tumor cells in astrocytoma include the undifferentiated, pre-astrocyte,as-trocyte gemistocyte and tumor giant cells.Some similarities were found between the uItrastructure of as-trocytoma and that of the developing astrocyte,the tumor cells somewhat resembling the cells of devel-oping astrocytes.But certain differences were observed,the tumor cells were usually polymorphic with increased chromatin in nucleus,and asynchronism between nucleus and cytoplasm differentiation was sometimes found.The current nomenclature and classification of ast rocvtoma were evaluated and dis-ussed,the author's opinion on classification was presented.