血清同型半胱氨酸在不稳定型心绞痛危险度分层中的作用

Effects of serum homocysteine on risk classification of unstable angina pectoris

目的观察血清同型半胱氨酸(Hcy)在不稳定型心绞痛(UAP)危险度分层中的作用。方法对UAP患者168例,稳定型心绞痛(SAP)患者98例和正常对照组54例,分别测定空腹静脉血清Hcy浓度,按照文献[1]的分层,将UAP分为低、中、高危险组,比较各组间的差异。结果UAP组Hcy水平高于对照组和SAP组(P<0.05),低、中、高危险组的Hcy水平逐步升高(P<0.05)。结论血清Hcy水平是UAP患者危险度分层的重要指标。

Objective To study the effect of serum homocysteine(Hcy) on risk classification of unstable angina pectoris(UAP).Methods The serum Hcy levels in 168 patients with UAP,98 with stable angina pectoris(SAP)and 54 heattby controls were determined.According to the classification in the 'Guide' , the patients with UAP were divided into low,moderate and high sk groups. Hcy levels were detected in morning and their differences were compared between these groups.Results The serum Hcy level in patients with UAP was higher than those in patients with SAP and healthy controls (P<0.05).Hcy increased with increasing risk(P<0.05).Conclusion The serum Hcy level can be used as an index for the risk classification of UAP.