摘要
对汕头地区1971~l992年临床疑似脊髓灰质炎(灰髓炎)417例患者粪便标本和94例患者双份血清,进行了病毒病因检测,结果分离出病毒192株,检出率为46.0%,计有灰髓炎病毒156株,其中Ⅰ型病毒138株,占灰髓炎阳性的88.5%。柯萨奇病毒10株,埃可病毒和腺病毒各8株,肠道71型病毒7株,未定型病毒3株。对114株灰髓炎Ⅰ型病毒进行了型内抗原分析,结果表明,不同时期分离的灰髓炎Ⅰ型病毒其抗原性有明显差异。在1989年以前分离到的灰髓炎Ⅰ型病毒,不论是流行期还是散发病例,均以灰髓炎野毒变异株为主,而1989~l992年流行的灰髓炎Ⅰ型病毒株则以野毒株Mahoney株及其变异株为主要流行毒株。
iral studies were done on 4 1 7 cases,suspected of poliomyelitis in Shantou area from l9 71~1992 inclusive.Altogether stool samples from 4 1 7 cases,and sera from 94 cases were collected.The result showed that l9 2 of these cases were positive for viral isolation,the positive ratc was 46%. Among these,there were l5 6 strains of poliovir- uses,10 of coxsackie viruses,8 ECHO viruses,8 adenoviruses,7 Enteroviruses 71 and 3 strains undefined.The subtype antigen of 114 poliovirus I strains analysed was the result showed that the antigenicity of the isolated polioviruses I was distinctly different in different periods.Before l989 the polioviruses l were mainly wild strains, no matter whether it was isolated in epidemics or in sporadic period,from l989 to l992 the isolated pol ioviruses I were mainly Mahoney wild strains and its variant strains.
出处
《中华传染病杂志》
CAS
CSCD
北大核心
1995年第1期33-35,共3页
Chinese Journal of Infectious Diseases
关键词
脊髓灰质炎
病毒
抗体
抗原
病因
汕头地区
Poliomycl itis
Viral isolation
Neutralizing antibody
Antigen analysis