β-环糊精-H_2O_2存在下极谱催化法测定六次甲基四胺

Polarographic determination of hexamethylenete tramine in the presence of β-cyclodextrin and hydrogen peroxide

建立了在氧化剂存在下利用分子识别测定六次甲基四胺的电化学分析方法。在KH2PO4 Na2HPO4(pH6.24) β环糊精(βCD)的支持电解质中,六次甲基四胺与βCD形成的包合物于-0.80V(vs.SCE)电位处产生一极谱还原波;加入H2O2后,该还原波的峰电流增加约10倍,峰电位基本不变,产生了一较灵敏的极谱催化波。其二阶导数峰电流ip″与六次甲基四胺浓度在4.0×10-6～5.0×10-4mol/L范围内呈良好线性关系(r=0.9990,n=8),检出限为2.0×10-6mol/L。该方法可用于工业乌洛托品和树脂样品中六次甲基四胺的测定。

<Abstrcat>The reduction wave of Hexamethylenetetramine-β-CD appeared at ca. (0.80 V (vs. SCE) in 0.05 mol/L KH_2PO_4-Na_2HPO_4 (pH 6.24) solution. In the presence of H_2O_2, the reduction wave is catalyzed to produce a parallel catalytic wave. Based on the catalytic wave, a novel method for the determination of hexamethylenetetramine is proposed. The peak current of the catalytic wave is rectilinear over Hexamethylenetetramine concentration in the range 4.0×10^(-6)～5.0×10^(-4) (mol/L). The peak current of the catalytic wave is ca. 10 times higher than that of the corresponding reduction wave. The detection limit is 2.0×10^(-6) mol/L. The proposed method can be applied to the direct determination of Hexamethylenetetramine in industrial products.