维吾尔族胃癌138例临床分析

Clinical analysis of 138 cases of Uygur patients with stomach cancer

目的:探讨本地区的维吾尔族(维族)胃癌的发病情况、临床病理特点。方法:回顾分析1995年1月～2003年12月在我院住院治疗的维族胃癌患者138例,汉族胃癌患者356例。结果:胃癌发病情况:男性多于女性,维族胃癌患者发病人数少于汉族,41～50岁年龄段维族胃癌患者发病人数显著高于同年龄段的汉族患者(x2=6.3935.P<0.05).60岁以上患者中汉族患者发病人数多于同年龄段的维族患者.且差异均有统计学意义(x2=3.9963,P<0.05);维族胃体癌发生率明显高于汉族.差异有统计学意义(x2=5.0553,P<0.05);而汉族胃窦癌发生率明显高于维族,差异有统计学意义(x2=12.4152,P<0.05)。结论:维族胃癌发病人数少于汉族,维族及汉族胃癌发病情况与一般胃癌发病危险因素的流行病学特点不同,原因有待分子遗传学方面的研究来证实。

Objective: To investigate the morbidity status, clinical and pathological characteristics of stom ach cancer of Uygur patients in Xinjiang. Methods: One hundred and thirty-eight cases of Uygur patients and three hundred and fifty-six cases of Han patients with stomach cancer, who were treated in our hospital during 1995-2003, were analyzed retrospectively. Results: The incidence was significantly higher in male patients than in female patients, and obviously lower in Uygur patients than that of Han patients; and significantly higher in Uygur patients aged from 41-50 years old than in Han patients at the same ages (21.7% vs 12. 6%); but higher in Han patients over 60 years than in Uygur patients at the same ages (42. 4% vs 32. 6%). There were significances in statistics. The incidence rate of cancer of stomach body in Uygur patients was significantly higher than that in the Han patient (55. 1 % vs 43. 8% ) , there was significance in statistics. The incidence rate of cancer of stomach sinus in Han patients was higher than that in Uygur patients (34. 3% vs 18. 1%), but there was no significance in statistics. Conclusions: The incidence of stomach cancer in Uygur patients was significantly lower than that in Han patients. The incidence of stomach cancer in Uygur and Han nationality in Xinjiang is different from the risk factor and epidemiologi cal characteristics of general incidence of stomach cancer. It needs confirming by study of molecular genet ics.