摘要
喉曲菌病极为罕见。报告6例喉曲菌病,其临床特点是:①患者健康状况良好;②声嘶是唯一首发症状;③声带见白色附着物;④活检为化脓性、肉芽性及坏死性炎症,组织内见珊湖状分枝分隔菌丝及孢子;⑤真菌培养长出烟色曲菌菌落,镜检见分枝分隔菌丝及烧瓶样顶囊,顶生性小梗及孢子;⑥用酮康唑、或伊曲康唑治愈,经长期随访均无复发。讨论了病因,诊断及治疗问题。
Aspergillosis of the larynx is extremely rare.Six cases of aspergillosis of the larynx were presented.Clinical characters of the patients were as follows:(1) their physical conditions were excel-lent;(2) Hoarsenes was the first symptom;(3) true vocal cord demonstrated white mass;(4)Biopsy of the lesion revealed suppurative, granulomatous and necrotic inflammation with hyphae and spore with in the tissue;(5) Culture of fungi displayed tobaco colour colonies of aspergillus. microscspic examina-tion demontrated spore and septate hyphae with coral-shape dichotomous banching and flask-shape vesi- cle with phialide and spore on top;(6) All patients were cured with Ketoconazol and ltraconazol without recurrence for long-term follow-up. Etiology, diagnosis and therapy of aspergillosis of the larynx were discussed.
出处
《中华耳鼻咽喉科杂志》
CSCD
1995年第2期111-113,共3页
Chinese Journal of Otorhinolaryngology
关键词
喉疾病
曲霉菌病
药物疗法
Laryngeal diseases Aspergillosis Drug therapy