食用香料4-甲基-2-戊基-1,3-二氧戊环的合成

Study on the Synthesis of Flavor 4-methy-2-pentyl-1,3-dioxolane

文中以己醛和1,2-丙二醇为原料,用柠檬酸作催化剂,环己烷作带水剂,合成了食用香料4-甲基-2-戊基-1,3-二氧戊环。采用了正交试验对反应条件进行了优化,己醛与1,2-丙二醇的摩尔比值为0.3∶0.21,柠檬酸与己醛的摩尔比值为0.02,反应时间为120min,产率为87.2%,采用红外光谱和气-质联用分析手段对产物进行了结构确定。

Flavor 4-methyl-2-pentyl-1,3-dioxolane was prepared by reaction of n-hexyl aldehyde and 1,2-propanediol in the presence of citric acid as the calalyst. Based upon orthogonal experimental design, the optimized reaction conditions were : the mole ratio of n-hexyl aldehyde to 1,2-propanediol was 0.3 to 0.21, and the mole ratio of citric acid to n-hexyl aldehyde was 0.02; the reaction lasted 120 min with the removal of water by cyclohexane. The yield of 4-methyl-2-pentyl-1,3-dioxolane was 87.2%.The finished product was analyzed and confirmed by IR and GC-MS.