1Vaux D,Cory S,Adams JM,et a1. bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to im mortalize pre-B cells[J].Nature,1988,335:440-442.
2[1]Kleihues P, Cavenee WK. Pathology and genetics of tumors of the nervous system-World Health Organization of tumors. IARC press ,Lyon, 2000.
3[2]Korsmeyer SJ. Bcl-2 initiate a new category oncogenes: regulators of cell death. Blood, 1992,80(4) :879-886.
4[3]Hockenberg DM, Ol tval ZN, Yin XM, et al. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell, 1993,75 (1):241-251.
5[4]Fernandez-sarabia MJ, Bischoff JR. Bcl-2 associates with the res-related protein R-ras p23. Nature, 1993,366 (1): 275-277.
6[5]Lan M, Dubyak G, Chen L, et al. Evidence that bcl-2 represses apoptosis by regulating endoplasmic reticulum associated Ca fluxes. Proc Acad Sci USA,1994, 91(6):6569-6573.
7[6]Hockenberg DM, Zutter M, Hichey W, et al. Bcl-2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proc Acad Sci USA,1991,88(6) :6961-6965.
8[7]Alderson LM, Castleberg RL, Harsh Ⅳ, et al. Human gliomas with wild-type P53 express bcl-2 . Cancer Res,1995,55(4):999-1001.
9[8]Schluter MD, Rang A, Wiester OD. Apoptosis and apoptosis-related gene products in primary non-Hodgkin's lymphoma of the central nervous system. Acta Neuropathol, 1998,96( 1 ): 157-162.
10[9]Roth W, Weller M. Chemotherapy and immunotherapy of malignant glioma :molecular mechanisms and clinical perspectives. Cell Mol Life Sci,1999,56(5):481-506.
1Qing Wang~1 Zhi Ying Lin~2 Xiao Li Feng~3 ~1Department of Microbiology,Medical Center of Fudan University.the former Shanghai Medical University,Shanghai 200032,China ~2Liver Cancer Institute,Zhongshan Hospital,Shanghai 200032,China ~3Shanghai Institute of Biochemistry,Academy Sinica,Shanghai 200031,ChinaQing Wang earned master degree from Shanghai Medical University in 1996,now a senior lecturer of microbiology,specialized in the role of oncogcncs on tumor metastasis,having 8 papers published..Alterations in metastatic properties of hepatocellular carcinoma cell following H-ras oncogene transfection[J].World Journal of Gastroenterology,2001,7(3):335-339. 被引量：48
