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异丙酚联合芬太尼或瑞芬太尼静脉麻醉用于结肠镜检查的疗效观察 被引量:2

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摘要 目的观察异丙酚联合芬太尼或瑞芬太尼静脉麻醉用于纤维结肠镜检查的临床效果。方法60例需行纤维结肠镜检查的患者随机分为3组,每组20例。治疗组1给予异丙酚静脉注射,治疗组2给予芬太尼0.1μg·kg-1静脉注射+异丙酚静脉注射,治疗组3给予瑞芬太尼0.2μg·kg-1·min-1微泵维持+异丙酚静脉注射,待患者进入4级镇静状态时开始进镜,肠镜进入回盲部开始退镜时停止用麻醉药。观察3组患者的麻醉时间、异丙酚用量,记录检查前、进镜时、肠镜进入肝曲时和检查结束时血氧饱和度、心率、收缩压、舒张压和停用麻醉药后睁眼时间、定向恢复时间、呼吸抑制发生例数。结果治疗组1异丙酚用量最大;治疗组3血流动力学波动最大。但3组均在正常范围。治疗组3睁眼时间、定向恢复时间最短。3组间呼吸抑制差异无显著性。结论纤维结肠镜检查静脉麻醉时异丙酚联合芬太尼或瑞芬太尼能减少异丙酚用量,联合瑞芬太尼时能使患者苏醒时间缩短,但使用过程中应注意患者血流动力学变化。
出处 《医药导报》 CAS 2005年第8期695-696,共2页 Herald of Medicine
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