中国人主要脏器重量参考值

Reference values of main internal organs for Chinese

本文作者收集了我国建国以来各主要医学院校解剖教研室和病理教研室、法医研究所及医院病理科的尸解记录，根据参考值应取自正常健康人的原则，提出资料的选择标准，按标准从中选择了８２７３例发育正常的急死者的正常脏器，按男、女分１６个年龄组对其１２个脏器（脑、心、肾、肝、肺、胰、脾、肾上腺、甲状腺、胸腺、脑垂体、睾丸）的重量进行了统计分析。为了解国人脏器重量的长期增长趋势，将１９７０年前和１９７０年后的尸解脏器重量作了统计对比。在此基础上根据国人脏器重量增长的年龄阶段性，性别差异，长期增长趋势，和使用方便等原则，用内插三次样条近似函数曲线方法推荐了中国男、女各代表年龄组（０，１，５，１０，１５，２０～５０）的１２个脏器重量的参考值。同时用脏器重量与体重的回归方程计算了成人参考体重下各脏器重量的预期值。比较表明预期值与参考值非常接近，证明所推荐的脏器重量参考值的合理性。最后对推荐的中国人脏器重量参考值与现行ＩＣＲＰ和日本参考人值作了比较。

Data on the mass of internal organs were obtained from measurements in autopsies performed in main medical institutions of China in 1950-1990. A total of 8273 cases who were considered to be normal developed and sudden death were chosen for analysis according to the criteria proposed for choice of subjects.The average weights and standard deviations of 12 internal organs(adrenal gland,brain, heart, kidneys ,liver, lungs, pancreas, pituitary, spleen, testes, thymus,thyroid) were calculated for both sexes and 16 age groups and the cubic spline approximation curves of organ growth with age were drawn by using Stata software.Considering age stages, sex difference, long-term trend on organ growth and convenience for application, a series of reference values of 12 organs were proposed for both sexes of various ages (0, 1, 5, 10, 15, 20-25) by means of interpolating the curves of cubic spline approximation of each organ. Also the predictive values of mass of organs were calculated by regression equations of mass of organs with body weights and compared with proposed reference values. The results are very similar between them, implying that the reference values proposed here are reasonable and matchable with the reference value of body weights.Comparisons of proposed reference value of internal organs for Chinese were made with ICRP and Japanese Reference Man.