乙型肝炎病毒宫内感染的高危因素

High risk factors relating to intrauterine fetal infection of hepatitis B virus

用流行病学调查的病例对照方法对５７６例乙型肝炎病毒表面抗原（ＨＢｓＡｓ）（＋）孕妇的１６项危险因素进行研究，计算相对危险度比数比。结果：孕妇乙型肝炎病毒ｅ抗原（ＨＢｅＡ）（＋）、胎儿宫内窘迫、头盆不称是乙型肝炎病毒（Ｈ８ｖ）宫内感染的高危因素。此外，孕妇年龄、胎儿性别、孕妇甲胎蛋白（ＡＦＰ）水平，第一产程时间长短、胎盘体积和脐带长度等，也可能是有关因素。

ive hundred and seventy-six hepatitis B suface antigen(HBsAg)(+)gravidas were divided into one group ll0 cases of hepatitis B virus (HBV) DNA(+)and the other 466 HBV DNA(一)according to HBV DN A in t lie serum of t he u mbilical vessels。 The case cont roled st ud y methed was used to ana lyze l 6 risk factors,and the odd ratio was calculated. It revealed that high risk factors of intrauterine HBV infection were:hepatitis B antigen e (HBeAg)(+)of gravidas,fetal distress,and cephaIopelvic disprOportion。 In addition, gravidas age,fetal sex,quantity of alpha fetoprotein(AFP)in gravidas serum,duration of first stage of labor, placental volume,Iength of the umbilical cord etc,might also be related high risk factors.