含铜硅胶V形宫内节育器使用年限的研究

A Study on Duration of Using VCu200 Intrauterine Device

分析因各种原因取出的放置不同年限的含铜硅胶Ｖ形宫内节育器（ＶＣｕ２００ＩＵＤ）６６６个，观察其铜丝不完整率和铜丝的腐蚀、耗铜、释铜、铜段脱落以及ＶＣｕ２００ＩＵＤ的制作材料变化。结果：ＶＣｕ２００ＩＵＤ放置５～１０年和１０～１５年之间银丝不完整率分别为１２．３６％、２５．５３％，二者差异有显著性（Ｐ（０．００１）；整段铜丝脱落率分别为２．５４％、９．５７％，二者差异有显著性（Ｐ＜０．０５）。耗铜和释铜，６～１０年为３９．７３％，每日２２．９５μｇ。因腐蚀致使铜丝断裂最早发生于放置３年，整段铜丝脱落最早发生于放置５年。提示：ＶＣｕ２００ＩＵＤ以放置１０年为宜。

bjective To make certain of the duration of using V-copper 200mm￣2 intrauterine device(VCu200 IUD)。Methods Six hundreds and sixty six pieces or VCu200 IUD used for different time period and removed for various reasons were analyzed.The life span of VCu 200 IUD depended on corrosion,fragmentation and damage of copper wire and these parameters were measured on VCu 2 00 IUD re-moved.Results There were significant difference in copper wire fragmentation rate between tenth year-group and fifteenth year group which were 12.36%,25.53% respectively (P<0.001),and so were the expulsion rate of copper wire 2.54%,9.57% respectively(P<0.05).The copper loss and cop-per releasing rate in tenth year-group were 39.73%,22.95μg/day respectively; Copper corrosion re-sulted in fragmentation of copper wire which occurred the earliest in three years of use and expulsion of copper wire segment occurred after five years of use.Conclusion Comparing the above results with other copper intrauterine devices, it was suggest-ed that the suitable duration of VCu200 IUD use was ten years.