摘要
回顾分析1980~1994年收治的15例女性生殖系统原发性恶性淋巴瘤,7例发生于宫颈,2例发生于阴道,3例发生于卵巢,另外,外阴、子宫内膜和盆腔各1例。分别给予综合治疗,8例行放疗加化疗,3例行手术加放疗加化疗,3例卵巢恶性淋巴瘤行手术加化疗,1例盆腔恶性淋巴瘤行手术加放疗。结果:2例生存>5年,3例生存>3年,6例1年内恶化或死亡,4例治疗后不到2年,仍在随访中。提示:卵巢恶性淋巴瘤较生殖系其它部位的淋巴瘤预后差。化疗-放疗-化疗的序贯治疗适合于宫颈、阴道、外阴的淋巴瘤治疗;对于高度恶性的淋巴瘤应选择高强度的化疗,对伴有较大宫颈肿瘤的患者,应及早放疗。
Objective To review fifteen cases with primary malignant lymphoma of the female genitaI tract at Cancer Hospital,Chinese Academy of Medical Sciences from 1980~1994。Methods This is a clinical retrospiective analysis.There were 7 cases of lymphoma originating in the cervix,2 in the vagina,3 in the ovary,1 in the vulva, endometrium and pelvic cavity respectively.All of the 1 5 cases were given combination therapy. 3 ovarian lymphoma were treated by surgery and chemotherapy, 2 cervical lymphoma and 1 endometrial lymphoma by surgery, chemotherapy and radio-therapy,1 pelvic lymphoma by surgery and radiotherapy,others by radiotherapy and chemotherapy;Results Two patients are living more than 5 years,3 patients more than 3 years。 4 patients were followed up for less than 2 years and 6 patients relapsed or died。Concl usions The prognosis of ovarian lymphoma is worse than that of other genital sites。 Con-binel and sequential chemotherapy-radiotherapy-chemotherapy is the proper treatment sequence for lym-phoma of the cervix, vagina and vulva, Extensive chemotherapy may be an appropriate choice for highly malignant pathologicaI type,Radiation should be given early for large cervical lymphoma.
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
1995年第10期614-617,共4页
Chinese Journal of Obstetrics and Gynecology
关键词
淋巴瘤
女性生殖器肿瘤
放射疗法
药物疗法
Lymphoma Genital neoplasms,female Radiotherapy Chemotherapy,pharmaceutical