医院内肺部真菌感染的临床分析

Clinical Research on Pulmonary Fungus Enfection Inter-Hospitalization

目的:引起临床医师对医院内肺部真菌感染(PFIH)的高度重视。方法:对56例医院内肺部真菌感染的病例进行临床分析。结果:45例患者均患有慢性肺部疾病,其中以慢性阻赛性肺病、慢性肺原性心脏病导致的PFIH最多占68%。住院日的延长,广谱、多种抗生素的长时间应用,精皮质激素和免疫抑制剂的使用,是PFIH常见的医源性因素。痰培养念珠菌属占91%,特别是白色念殊菌即占82%。

Objective : The incidence rate of pulmonary fungus infection in-hospitalization ( PFIH ) is going on in recent years, which should draw attention to clinical doctors. Methods: Clinical data of 56 patients with PFIH was analysed. Results : The patients all suffered from chronic pulmonary diseases of which COPD and Cor pulmonale constituted 68%. Some medical factors were common, such as the prolonged hospilalization, long using of the multiple broad spectrum antibiotis, adrenocortical and incmunosuppresser . In the sputum culture bacteria , pulmonary candidiasis constituted 91%,particularly the Candida albicans , which accounting 82% . Conclusion: The data suggest that some factors resulting in PFIH should be decreased and avoided possibly in order to prevent PFIN.