肾功能衰竭继发甲状旁腺机能亢进的核素甲状旁腺显像诊断

Diagnosis of secondary hyperparathyroidism with ￣(99m)Tc-MIBI/￣(131)I parathyroid imaging in chronic renal failure

应用９９ｍＴｃ－甲氧基异丁基异腈（ＭＩＢＩ）和１３１Ｉ甲状旁腺显像对２０例慢性肾功能衰竭病人和１５例健康者进行了检查，并测量其血清甲状旁腺素（ＰＴＨ）浓度．结果：２０例肾衰患者均显示甲状旁腺增大；ＰＴＨ浓度肾衰组为８００．４７±６６５．２５ｐｍｏｌ／Ｌ，对照组为８２．８１±１３．７９ｐｍｏｌ／Ｌ．结果提示甲状旁腺显像和ＰＴＨＲＩＡ可为继发性甲状旁腺机能亢进的诊断提供有价值的资料．

Abstract chronic renal failure (CRF) patients and 15 normals were investigated with radionuclide parathyroid imaging and parathyroid hormone (PTH) RIA measurement for the detection of hyperparathyroidism.The serum PTH concentrations were 800.47±665.25pmol/L and 82.81±13.79pmol/L in two groups respectively. The radionuclide parathyroid images revealed that 1～4 enlarged parathyroid glands were visualized in the CRF patients,none in the normals.