生血胶囊耐缺氧效应的研究

Effct of Blood-Replenishing Capsule on tolerance to anoxia

目的:观察生血胶囊(黄芪、仙鹤草、人参等)对缺氧动物的保护作用,为预防或降低高原反应发生率,提高高原部队的战斗力提供科学依据。方法:分别采用常压和化学药品致动物缺氧,观察生血胶囊对小白鼠密闭缺氧存活时间的影响,测定其血红蛋白含量和小鼠脑组织中SOD、MDA含量。结果:生血胶囊可以显著延长小鼠的密闭缺氧存活时间,其机制与明显促进小鼠血红蛋白的合成,降低总耗氧量,增加脑组织中SOD而减少MDA含量有关。结论:生血胶囊有良好的耐缺氧作用。

AIM To explore the protection effect of Blood-Replenishing Capsule (BRC) on hypoxic animals in order to lower the rate of altitude stress. METHODS Comparison of BRC on survival time of mice under ordinary pressure and chemical hypoxia were observed and the oxygen consumption was measured. RESULTS BRC-obviously prolonged the survival time of hypoxic mice, reduced the oxygen consumption and increased the hemoglobin (Hb) content in the bloods.Mouse brain's SOD was obviously higher and MDA concetration remarkable lower in BRC groups than those in control groups. CONCLUSION BRC shows remarkable effect on hypoxia tolerance in mice.