期刊文献+

大剂量甲基强的松龙治疗脊髓损伤的观察及护理 被引量:1

Observation and Nursing of Spinal Injury Treatment with Large Dose Methylprednisolone
下载PDF
导出
摘要 目的观察大剂量甲基强的松龙两种给药法治疗脊髓损伤的疗效和护理,探讨用药特点及护理对策。方法78例脊髓损伤手术后的患者,按治疗方法的先后分为常规法(34例),改良法(44例),根据脊髓损伤的神经功能评分标准,评定脊髓损伤程度并比较疗效,记录用药特点及用药后临床表现。结果两种方法治疗后感觉及运动功能均有改善,但改良法对感觉、运动功能的改善明显优于常规法(P<0.01)。结论甲基强地松龙可改善脊髓损伤患者的运动及感觉功能,采取改良给药方法,加强护理和观察,能使甲基强的松龙发挥最大的药理作用和疗效。减少并发症的发生。 Objective To observe the therapeutic effects and the nursing of two dose regimens in treating spinal injury with large dose methylprednisolone. Methods 78 cases of postoperative patients with spinal injury were divided into two groups, the normal treatment group included 34 cases and the reforming group included 44 cases. The spinal injury degree and therapeutic effect were evaluated according to nerve function scores, the medication characteristics and manifestations after medication were recorded. Results The sensory and motor function was improved after two kinds of medication, the improving of sensory and motor function with the reforming method was superior to that of the normal methods (P<0.01). Conclusions Methylprednisolone can improve the sensory and motor function of spinal injury patients. With reforming methods, enhancing nursing and observation can make methylprednisolone have the maximal therapeutic effect, decrease complications.
出处 《现代护理》 2005年第10期794-795,共2页 Modern Nursing
关键词 甲基强的松龙 脊髓损伤 治疗 护理 Methylprednisolone Spinal injury Therapeutic Nursing
  • 相关文献

参考文献5

二级参考文献39

  • 1王彤,励建安.脊髓损伤的神经和功能分类标准(一)[J].中国脊柱脊髓杂志,1994,4(2):80-81. 被引量:61
  • 2王彤,励建安.脊髓损伤的神经和功能分类标准(二)[J].中国脊柱脊髓杂志,1994,4(3):138-140. 被引量:23
  • 3[1]Aarsman AJ,Ransohoff J,Hunt WE et al.Lipocrtin inhibition of extracelluar and intracelluar phospholipase A2 is substrate concentration dependent[H].FEBS Lett,1987,219:176-180.
  • 4[2]Anderson DK,Braughler JM,Hall ED et al.Effects of treatment with U-74006F on neurological outcome following experimental spinal cord injury[J].J Neurosurg,1988,69:562-567.
  • 5[3]Anderson DK:Iron-induced lipid peroxidation in spinal cord:protection with mannitol and methylprednisolone[J].J Free Radic Biol Med.1985,1:59-64.
  • 6[4]Anderson DK,Means ED.Lipid hydrolysis and peroxidation in injuried spinalcord:portial protection with methylprednisolone or vitamine E and slenium[J].Cent Nero Syst Trauma,1985,2:257-267.
  • 7[5]Anderson DK,Means ED,Waters TR et al.Microvascular perfusion and metalolism in injured spinal cord after methylprednisolone treatment[J].J Neurosurg,1982,56:106-113.
  • 8[6]Andrew CB,Myers RA,Ducker TB.Molecular mechanisms of anti-inflammatory action of glucocorticoids[J].Bio Essays,1996,18:371-378.
  • 9[7]Behrmann DL,Bresnahan JC,Beattie MS.Modeling of acute spinal cord injury in the rat:neuro-protection and enhanced recovery with methylprednisolone,U-74006F and YM-14673[J].Experimental Neurology,1994,126:61-75.
  • 10[8]Bracken MB,Shepard MJ,COllins WF,et al.A randomized controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury[J].The New England J of Medicine.1990,322:1405-1411.

共引文献40

同被引文献5

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部