性病患者支原体检测及药敏结果分析

The Detection on Mycoplasma Infection and the Analysis of Drug Susceptibility in Patients with STD

目的了解STD门诊患者支原体感染及耐药情况。方法对423例STD门诊患者进行支原体培养,并对阳性标本做抗生素药敏试验。用支原体培养、鉴定、药敏一体化试剂盒进行检测。结果423例中支原体阳性155例,阳性率36.6%,其中男性阳性率28.3%,女性阳性率50.6%,支原体感染率在男女性别之间有显著性差别(χ2=21.26,P<0.005)。解脲支原体(UU)、人型支原体(MH)及UU+MH混合感染阳性率分别为27.2%、2.6%和6.9%。UU对10种药物敏感性最高的是交沙霉素(100%),其次是阿奇霉素(99.1%)。结论性病患者支原体感染率高达36.6%,主要为UU引起占74.2%;交沙霉素是治疗泌尿生殖道UU感染的首选药物,其次是阿奇霉素。

Objective To learn the mycoplasm infection and the drug resistance in out patients with STD. Methods Mycoplasma culture was carried out with the samples of 423 cases and then the susceptibility of mycoplasma to antimicrobial agents were done on the positive samples. The culture, identification and the drug resistance of mycoplasma were carried out with one complex mycoplasma Kit. Results 155 of 423 cases were infected with mycoplasma. The total positive rate was 36.6%, male positive rate of mycoplasma was 28.3% and female was 50.6%. Infection,s rate of mycoplasma had obvious statistical difference between males and females(χ~2=21.26,P<0.005). The positive rate of UU, MH and mixed both infection were 27.2%、2.6% and 6.9. The highest susceptibility rate of UU to ten kinds of antimicrobial agents was Jos(100%), the second was Azi(99.1%). Conclusion Mycoplasma infection rate is 36.6% in patients with STD, major mycoplasma is UU74.2%; Jos is the first choice to treat urogenital tract infection UU, the second is Azi.